Human Papilloma Virus Infection in Head and Neck Cancer

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Human papilloma virus infection in head and neck cancer.

BACKGROUND The causal link between cervical cancer and human papilloma virus (HPV) is well known. It is now becoming clear that some types of squamous-cell carcinoma of the head and neck, particularly oropharyngeal carcinoma (OPC), are also linked to HPV infection. The development of vaccines against certain HPV genotypes has changed the management strategy for HPV-associated diseases of the ut...

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human papilloma virus in head and neck squamous cell cancer

background: epidemiologic and molecular evidences have established a strong link between high risk types of human papilloma virus and a subgroup of head and neck squamous cell carcinomas (hnscc). we evaluated the frequency of hpv positivity in hnscc and its relationship to demographic and some risk factor variables in an open case- control study. methods: fourteen recently diagnosed patients wi...

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Human Papilloma Virus in Head and Neck Squamous Cell Cancer

BACKGROUND Epidemiologic and molecular evidences have established a strong link between high risk types of Human Papilloma Virus and a subgroup of Head and Neck Squamous Cell Carcinomas (HNSCC). We evaluated the frequency of HPV positivity in HNSCC and its relationship to demographic and some risk factor variables in an open case- control study. METHODS Fourteen recently diagnosed patients wi...

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Occurrence of p53 gene deletions and human papilloma virus infection in human head and neck cancer.

Little is known regarding the molecular genetic events in head and neck carcinoma. Epidemiological evidence suggests that both alcohol and tobacco use are related to the development of these neoplasms, and viral infections have also been postulated to play a role in some tumors. Loss of p53 tumor suppressor gene function has been found in many malignancies and can occur through either gene muta...

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Human Papilloma Virus-Induced Head and Neck Cancer

Head and neck cancers are a common spectrum of diseases, accounting for over one-third of a million deaths worldwide each year, and over 11,000 annual US deaths. This has typically been thought of as a disease related predominately to lifestyle choices, specifically to heavy exposures to tobacco and alcohol, and as such, has been diagnosed more in older males than in females. With increased pub...

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ژورنال

عنوان ژورنال: Deutsches Aerzteblatt Online

سال: 2013

ISSN: 1866-0452

DOI: 10.3238/arztebl.2013.0184